
As the 2025–26 Fantasy Premier League season barrels forward, Gameweek 6 presents a fresh slate of opportunities and challenges for managers worldwide. After a start that has seen many deploy early Wildcards to course-correct, this weekend’s fixtures could be a pivotal moment. With tantalizing matchups spread across three days, identifying the right assets is more crucial than ever. FPL managers, brace yourselves – it’s time to fine-tune those squads!
This week, the spotlight shines brightly on Manchester City, whose home clash against Burnley looks set to be a goldmine for FPL points. But beyond the obvious, several other players are poised to deliver significant hauls. Here’s a breakdown of the top picks for Gameweek 6, designed to give you the edge.

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Goalkeepers: Banking on Clean Sheets
While guaranteed clean sheets are a rarity, a couple of custodians stand out for Gameweek 6:
- Gianluigi Donnarumma (£5.6m) – Manchester City: The Italian shot-stopper is a prime target. Manchester City’s home fixture against Burnley screams clean sheet potential. Donnarumma has already shown his FPL prowess, earning six points on his Premier League debut against Manchester United and narrowly missing another against Arsenal.
- Jordan Pickford (£5.5m) – Everton: A pricier option, but potentially worth every penny. Everton hosts a struggling West Ham United side on Monday night, who have lost five of their six outings this season. This fixture could yield not only a clean sheet but also valuable save points for the England international.
- James Tarkowski (£5.5m) – Everton: Mirroring Pickford’s appeal, Tarkowski is a fantastic option. Everton has already secured two clean sheets this season, and Tarkowski has consistently delivered bonus points for defensive contributions in all five of his appearances.
- Marcos Senesi (£4.8m) – Bournemouth: For those seeking value, Senesi is a revelation. He’s the second-highest scoring defender in FPL with 37 points, a testament to Bournemouth’s surprising defensive solidity. Facing a low-scoring Leeds United on Saturday, he’s a strong candidate for another haul.
- Virgil van Dijk (£6.1m) – Liverpool: After a crucial midweek rest, Van Dijk is always a safe bet. His goal threat from set pieces combined with Liverpool’s defensive prowess makes him a consistent performer, even against a tricky Crystal Palace away fixture.
- Manchester City Defenders: With the Burnley fixture, any City defender is a strong shout. While rotation is always a concern, Joško Gvardiol (£5.8m) and Rúben Dias (£5.5m) appear fairly nailed on to start.
- Tottenham Hotspur Duo: Against a Wolverhampton Wanderers side yet to pick up a point, Pedro Porro (£5.6m) and Micky van de Ven (£4.7m) offer significant upside.
- Mohammed Kudus (£6.6m) – Tottenham Hotspur: Fresh off two assists against Brighton, Kudus is in fine form. Alongside Xavi Simons (£7.1m), he could be central to Tottenham’s attack against Wolves.
- Manchester City Midfielders: While Pep Guardiola’s rotation policy keeps managers on their toes, Tijjani Reijnders (£5.6m) and Jérémy Doku (£6.4m) are expected to start after being rested midweek. Phil Foden (£8.0m), despite featuring in the Carabao Cup, delivered a goal and an assist, reminding everyone of his FPL potential.
- Premium Picks: Never ignore the FPL titans. Mohamed Salah (£14.5m) and Bruno Fernandes (£9.0m), despite challenging away trips to Crystal Palace and Brentford respectively, have combined for 56 points this season and possess the quality to deliver at any moment.
- Antoine Semenyo (£7.7m) – Bournemouth: The Premier League’s form midfielder, Semenyo has already amassed 41 points this term, seven more than any other midfielder. With hauls of 13 and 15 points already, he could be a differential against Leeds.
- Other Notables: Jack Grealish (£6.8m) and Iliman Ndiaye (£6.5m) impressed even in defeat last weekend and face West Ham at home. Morgan Gibbs-White (£7.5m) could also thrive against Sunderland.
- Erling Haaland (£14.3m) – Manchester City: The undisputed king. With six goals in five appearances, Haaland is in devastating form and is a near-mandatory captain, if not triple captain, pick against Burnley. Minor back injury concerns aside, he is simply too good to ignore.
- João Pedro (£7.8m) – Chelsea: Facing his former club Brighton at Stamford Bridge, Pedro will be highly motivated. With 35 points already this season, he could punish the Seagulls.
- Richarlison (£6.7m) – Tottenham Hotspur: Expected to return to the starting XI after a substitute appearance midweek, Richarlison’s early season form (three goals, one assist) makes him an excellent short-term pick against a Wolves side that has conceded three or more goals in three of their five league games.

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Defenders: Point Magnets and Budget Gems
Solid defensive picks can often be the unsung heroes of an FPL team:
Midfielders: The Engine Room of Points
Midfielders often provide the most explosive returns:

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Forwards: The Goal-Getters
Strikers are often the key to massive Gameweek hauls:

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FPL Deadline for Gameweek 6
Don’t get caught out! With no Friday night fixture, the deadline for Gameweek 6 is 11:00 a.m. BST on Saturday, 27 September. Ensure all your transfers, captaincies, and chip activations are confirmed before this time.

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This Gameweek offers a blend of reliable premium options and exciting differentials. Strategic planning, especially around the Manchester City assets, will be key to climbing those mini-league tables. Good luck, FPL managers!
For more in-depth analysis and expert tips, explore
BBC Sport’s Fantasy Football section.