
The NFL season is set to explode with an NFC East showdown as the reigning Super Bowl champion Philadelphia Eagles host their bitter rivals, the Dallas Cowboys, in the highly anticipated 2025 NFL Kickoff Game. This marquee matchup, scheduled for Thursday, September 4th, at Lincoln Financial Field, promises to deliver high-stakes drama and a thrilling start to the new campaign.

Super Bowl Champions Ready to Defend Their Crown
The Philadelphia Eagles enter the season fresh off a dominant 2024 campaign, which saw them post an impressive 14-3 regular-season record before culminating in a resounding 40-22 Super Bowl victory over the Kansas City Chiefs. Quarterback Jalen Hurts, a dual-threat sensation, and a formidable defense led by a relentless pass rush, have established the Eagles as a force to be reckoned with. Their home-field advantage is undeniable, boasting an 11-game winning streak at Lincoln Financial Field.
Cowboys Seek Redemption After a Challenging Season
Conversely, the Dallas Cowboys are eager to turn the page after a disappointing 7-10 season that saw them miss the playoffs. A significant blow came with quarterback Dak Prescott’s season-ending hamstring injury after just eight games. The offseason also brought a major roster shift, with star linebacker Micah Parsons traded to the Green Bay Packers. However, the Cowboys are optimistic about Prescott’s return and the addition of wide receiver George Pickens, who led the NFL in yards per reception (18.1) in 2023. Pickens will provide another elite target alongside the dynamic CeeDee Lamb, aiming to revitalize the Dallas offense.

A Historic Week 1 Rivalry Matchup
This Week 1 clash marks the first time these storied NFC East rivals have met in the opening week since 2000, adding another layer of intrigue to an already fiery matchup. The Eagles dominated the 2024 season series, sweeping the Cowboys with two blowout victories and outscoring them by a combined 75-13. Dallas will undoubtedly be motivated to avenge those losses.

Betting Odds and Expert Predictions
Kickoff is set for 8:20 p.m. ET on Thursday, September 4th. The Eagles are currently favored by 8.5 points in the latest Eagles vs. Cowboys odds at FanDuel Sportsbook, with the over/under for total points scored set at 47.5. Philadelphia’s money line stands at -433, while Dallas is at +335.
For those looking to place bets, the SportsLine projection model, which simulates every NFL game 10,000 times, offers valuable insights. This model has an impressive track record, up well over $7,000 for $100 players on top-rated NFL picks since its inception, including a stellar 31-15 record on top-rated picks in 2024. The model is currently leaning towards the Over on the point total and indicates one side of the spread is hitting in nearly 60% of simulations. You can find their complete picks at SportsLine.
Why the Eagles are Poised to Cover
- Dominant 2024 Series: Philadelphia’s two blowout wins over Dallas last season, outscoring them 75-13, highlight their superiority.
- Saquon Barkley’s Impact: New Eagles running back Saquon Barkley led the NFL in rushing attempts, rushing yards, and rushing yards per game last season, accumulating 2,504 yards. He faces a Cowboys defense that ranked fourth-worst in the NFL in rushing yards allowed per game.
- Jalen Hurts’ Dual Threat: Hurts added 630 rushing yards (42 ypg) in the 2024 regular season and 194 rushing yards (48.5 ypg) in the playoffs. He rushed for 56 yards on seven carries in his sole meeting with Dallas last season.
- Home Field Advantage: The Eagles are riding an 11-game home winning streak and have covered the spread in six of their last seven NFC East games.

Why the Cowboys Could Challenge the Spread
- Dak Prescott’s Return: The return of a healthy Dak Prescott is crucial for the Cowboys’ offense, which struggled significantly in his absence last season.
- George Pickens’ Deep Threat: The acquisition of wide receiver George Pickens, who led the NFL in yards per reception (18.1) in 2023 and caught 12 passes of 30-plus air yards, provides a potent deep threat alongside CeeDee Lamb.
- Eagles’ Secondary Concerns: The Eagles lost veteran cornerback Darius Slay, leaving them with either rookie Andrew Mukuba or the inexperienced Sydney Brown in a key defensive role.
- Divisional Success and Motivation: Dallas covered the spread in five of its final seven games last season and has won 14 of its last 20 divisional games outright. The desire to avenge their 2024 losses to the Eagles will be a strong motivator.
- Super Bowl Hangover Potential: Defending champions sometimes experience a “Super Bowl hangover,” a potential factor the Cowboys could exploit.

Final Thoughts: A Must-Watch Kickoff
This 2025 NFL Kickoff Game is more than just an opening night; it’s a statement game for both franchises. The Eagles aim to assert their dominance and begin their Super Bowl title defense strong, while the Cowboys are desperate to prove they are legitimate contenders in the NFC East. With star power on both sides and playoff implications looming even in Week 1, this promises to be an unforgettable start to the NFL season. Don’t miss the action on Thursday, September 4th!